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History of Glutamine


Glutamine is one of the 20 amino acids formed by the human body. It is considered a non-essential amino acid because it can be derived from glutamic acid, another member of the amino acid family. Both glutamine and glutamic acid can be found in protein-rich foods such as beans, red meat, nuts and fish. The body uses this amino acide to improve mental function, control blood sugar levels and maintain muscle mass, among other applications.

The physiological importance of the amino acid L- glutamine for promoting and maintaining cell func- tion is now widely accepted. The importance of gluta- mine to cell survival and proliferation in vitro was first reported by Ehrensvard et al. in 1949 but was more fully described by Eagle et al. in 1956 Glutamine had to be present at 10- to 100-fold in excess of other amino acids in culture and could not be replaced by glutamic acid or glucose. This work led to the devel- opment of the first tissue culture medium that con- tained essential growth factors, glucose, a mixture of 19 essential and non-essential amino acids at approximately physiological concentrations and a high concentration of glutamine

In chinese medicine

The Chinese has searched for  holistic solutions to increase natural hormonal changes found in healthy young men for thousands of years. Instead of any Western approach to interfere with the male body’s production of hormones with the benefits of synthetic drugs, chinese people tried to stimulate the natural hormone production. Instead of closing this vital role of floods the body with gonadal hormone replacement unit drugs, the Chinese knew tips on how to solve many diseases which has a single plant material and natural.

The plant can be found growing widely in arid climates on poor soils. It has been used by the Chinese plus Indians for thousands of years to address the low amounts of testosterone and has also been used by the best body builders as being a dietary supplement since the 1970′s.

In order to understand how a “non-essential amino acid” can attract so much attention it is necessary to understand where the term “non-essential” comes from. An amino acid is only considered essential if it is not possible for the body to make the particular amino acid when there is adequate supply of other “essential” amino acids. Since it is possible to make glutamine from many different amino acids, including glutamic acid, valine and isoleucine, it is not considered essential however the fact that the body has a number of ways to produce glutamine may serve to illustrate its importance.

Glutamine is also a precursor for many other amino acids; an important fuel for the immune system, the brain and gut mucosal cells, and it is at the heart of a mechanism controlling acid:base balance. It may also be a direct regulator of protein synthesis and regulation, thus glutamine is at the heart of a metabolic cross roads and its adequate supply is thus crucial for optimal functioning of the body.


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